8F0L

Crystal Structure of the Human T cell Receptor CD3(EPSILON) N-Terminal Peptide Complexed with ADI-26906 FAB

Summary for 8F0L

• Entry DOI: 10.2210/pdb8f0l/pdb
• Descriptor: ADI-26906 Fab Heavy Chain, ADI-26906 Fab Light Chain, T-cell surface glycoprotein CD3 epsilon chain, ... (5 entities in total)
• Functional Keywords: cd3 epsilon, antibody-antigen complex, membrane protein-immune system complex, immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 99683.03

Authors

Battles, M.B.,Welin, M. (deposition date: 2022-11-03, release date: 2023-03-29, Last modification date: 2023-10-25)

• Primary citation: Liu, C.Y.,Ahonen, C.L.,Brown, M.E.,Zhou, L.,Welin, M.,Krauland, E.M.,Pejchal, R.,Widboom, P.F.,Battles, M.B.; Structure-based engineering of a novel CD3 epsilon-targeting antibody for reduced polyreactivity.; Mabs, 15:2189974-2189974, 2023; PubMed: 36991534; DOI: 10.1080/19420862.2023.2189974

Experimental method

X-RAY DIFFRACTION (1.81 Å)