8EZI

A tethered niacin-derived pincer complex with a nickel-carbon bond in lactate racemase R98A/R100A variant modeled with separated sulfite and NPN

8EZI の概要

• エントリーDOI: 10.2210/pdb8ezi/pdb
• 分子名称: Lactate racemase, 1,2-ETHANEDIOL, SULFITE ION, ... (9 entities in total)
• 機能のキーワード: catalytic activity, isomerase activity, racemase and epimerase activity racemase acting on hydroxy acids and derivatives, isomerase, metal ion binding
• 由来する生物種: Lactiplantibacillus plantarum WCFS1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 48233.86

構造登録者

Gatreddi, S.,Hausinger, R.P.,Hu, J. (登録日: 2022-10-31, 公開日: 2023-01-25, 最終更新日: 2024-05-01)

• 主引用文献: Gatreddi, S.,Sui, D.,Hausinger, R.P.,Hu, J.; Irreversible inactivation of lactate racemase by sodium borohydride reveals reactivity of the nickel-pincer nucleotide cofactor.; Acs Catalysis, 13:1441-1448, 2023; PubMed: 37886035; DOI: 10.1021/acscatal.2c05461

実験手法

X-RAY DIFFRACTION (1.99 Å)