8EYV
Structure of Beetroot dimer bound to DFHO
Summary for 8EYV
Entry DOI | 10.2210/pdb8eyv/pdb |
Descriptor | RNA (45-MER), POTASSIUM ION, (5Z)-5-[(3,5-difluoro-4-hydroxyphenyl)methylidene]-2-[(E)-(hydroxyimino)methyl]-3-methyl-3,5-dihydro-4H-imidazol-4-one, ... (4 entities in total) |
Functional Keywords | rna, aptamer, fluorescence, turn-on, fluorogenic, fluorophore, g-quartet, g-quadruplex |
Biological source | synthetic construct |
Total number of polymer chains | 2 |
Total formula weight | 32804.94 |
Authors | Passalacqua, L.F.M.,Ferre-D'Amare, A.R. (deposition date: 2022-10-28, release date: 2023-05-31, Last modification date: 2023-10-25) |
Primary citation | Passalacqua, L.F.M.,Starich, M.R.,Link, K.A.,Wu, J.,Knutson, J.R.,Tjandra, N.,Jaffrey, S.R.,Ferre-D'Amare, A.R. Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture. Nat Commun, 14:2969-2969, 2023 Cited by PubMed: 37221204DOI: 10.1038/s41467-023-38683-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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