8EY2

Cryo-EM structure of SARS-CoV-2 Main protease C145S in complex with N-terminal peptide

Summary for 8EY2

Entry DOI	10.2210/pdb8ey2/pdb
EMDB information	28666
Descriptor	3C-like proteinase (1 entity in total)
Functional Keywords	covid19, mpro, main protease, cryo-em, 3cl, sars-cov-2, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2
Total number of polymer chains	4
Total formula weight	138269.48
Authors	Noske, G.D.,Song, Y.,Fernandes, R.S.,Oliva, G.,Godoy, A.S. (deposition date: 2022-10-26, release date: 2022-12-07, Last modification date: 2024-05-01)
Primary citation	Noske, G.D.,Song, Y.,Fernandes, R.S.,Chalk, R.,Elmassoudi, H.,Koekemoer, L.,Owen, C.D.,El-Baba, T.J.,Robinson, C.V.,Oliva, G.,Godoy, A.S. An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition. Nat Commun, 14:1545-1545, 2023 Cited by PubMed: 36941262 DOI: 10.1038/s41467-023-37035-5 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.5 Å)

Structure validation