8EV8

Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, closed state

8EV8 の概要

• エントリーDOI: 10.2210/pdb8ev8/pdb
• EMDBエントリー: 28595 28603 28611 28620 28621 28622
• 分子名称: Cyclic nucleotide-gated cation channel alpha-3, Cyclic nucleotide-gated cation channel beta-3, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: cnga3, cngb3, ligand-bound, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 276890.11

構造登録者

Hu, Z.,Yang, J. (登録日: 2022-10-20, 公開日: 2023-08-09)

• 主引用文献: Hu, Z.,Zheng, X.,Yang, J.; Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.; Nat Commun, 14:4284-4284, 2023; PubMed: 37463923; DOI: 10.1038/s41467-023-39971-8

実験手法

ELECTRON MICROSCOPY (3.11 Å)