8EUQ
Crystal structure of HLA-DRA*01:01/HLA-DRB1*04:01 in complex with c44H10 Fab
Summary for 8EUQ
Entry DOI | 10.2210/pdb8euq/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, c44H10 Fab light chain, Hemagglutinin HA1 chain,HLA class II histocompatibility antigen DR beta chain, ... (7 entities in total) |
Functional Keywords | mhc class ii, hla-dr, antibody, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 192812.35 |
Authors | Kassardjian, A.,Julien, J.-P. (deposition date: 2022-10-19, release date: 2023-04-19, Last modification date: 2024-10-09) |
Primary citation | Kassardjian, A.,Sun, E.,Sookhoo, J.,Muthuraman, K.,Boligan, K.F.,Kucharska, I.,Rujas, E.,Jetha, A.,Branch, D.R.,Babiuk, S.,Barber, B.,Julien, J.P. Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses. Cell Rep, 42:112391-112391, 2023 Cited by PubMed: 37053069DOI: 10.1016/j.celrep.2023.112391 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.09 Å) |
Structure validation
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