8ESI

Bile Salt Hydrolase from B. longum with covalent inhibitor bound

Summary for 8ESI

• Entry DOI: 10.2210/pdb8esi/pdb
• Descriptor: Conjugated bile acid hydrolase, (1R,3aS,3bR,5aR,7R,9aS,9bS,11aR)-1-[(2R)-6-fluoro-5-oxohexan-2-yl]-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-7-yl hydrogen sulfate (non-preferred name) (3 entities in total)
• Functional Keywords: bile salt hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Bifidobacterium longum
• Total number of polymer chains: 8
• Total formula weight: 285269.04

Authors

Walker, M.E.,Lim, L.,Redinbo, M.R. (deposition date: 2022-10-14, release date: 2023-11-01)

• Primary citation: Walker, M.E.,Lim, L.,Redinbo, M.R.; Structural diversity of bile salt hydrolases reveals rationale for substrate selectivity; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.35 Å)