8EQ6

PD1 signaling receptor bound to FAB Complex

8EQ6 の概要

• エントリーDOI: 10.2210/pdb8eq6/pdb
• 分子名称: Programmed cell death protein 1, Antibody FAB light chain, Antibody FAB heavy chain, ... (4 entities in total)
• 機能のキーワード: immune signaling receptor fab complex, signaling protein, signaling protein-immune system complex, signaling protein/immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 62302.29

構造登録者

Bjorkelid, C.,Paluch, C.,Robertson, N.J. (登録日: 2022-10-07, 公開日: 2023-10-11, 最終更新日: 2024-03-06)

• 主引用文献: Lippert, A.H.,Paluch, C.,Gaglioni, M.,Vuong, M.T.,McColl, J.,Jenkins, E.,Fellermeyer, M.,Clarke, J.,Sharma, S.,Moreira da Silva, S.,Akkaya, B.,Anzilotti, C.,Morgan, S.H.,Jessup, C.F.,Korbel, M.,Gileadi, U.,Leitner, J.,Knox, R.,Chirifu, M.,Huo, J.,Yu, S.,Ashman, N.,Lui, Y.,Wilkinson, I.,Attfield, K.E.,Fugger, L.,Robertson, N.J.,Lynch, C.J.,Murray, L.,Steinberger, P.,Santos, A.M.,Lee, S.F.,Cornall, R.J.,Klenerman, D.,Davis, S.J.; Antibody agonists trigger immune receptor signaling through local exclusion of receptor-type protein tyrosine phosphatases.; Immunity, 57:256-270.e10, 2024; PubMed: 38354703; DOI: 10.1016/j.immuni.2024.01.007

実験手法

X-RAY DIFFRACTION (1.65 Å)