8EPV

2.2 A crystal structure of the lipocalin cat allergen Fel d 7

8EPV の概要

• エントリーDOI: 10.2210/pdb8epv/pdb
• 分子名称: Fel d 7 allergen, ACETATE ION, 1,2-ETHANEDIOL, ... (5 entities in total)
• 機能のキーワード: lipocalin, fatty acid binding protein, calyx, allergen
• 由来する生物種: Felis catus (domestic cat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18205.54

構造登録者

Min, J.,Pedersen, L.C.,Geoffrey, M.A. (登録日: 2022-10-06, 公開日: 2023-04-05, 最終更新日: 2024-11-13)

主引用文献

Min, J.,Foo, A.C.Y.,Gabel, S.A.,Perera, L.,DeRose, E.F.,Pomes, A.,Pedersen, L.C.,Mueller, G.A.
Structural and ligand binding analysis of the pet allergens Can f 1 and Fel d 7.
Front Allergy, 4:1133412-1133412, 2023

PubMed Abstract: Pet lipocalins are respiratory allergens with a central hydrophobic ligand-binding cavity called a calyx. Molecules carried in the calyx by allergens are suggested to influence allergenicity, but little is known about the native ligands.

PubMed: 36960093
DOI: 10.3389/falgy.2023.1133412

実験手法

X-RAY DIFFRACTION (2.19 Å)