8EPQ
Cryo-EM structure of SARS-CoV-2 Spike trimer S2D14 with two RBDs exposed
Summary for 8EPQ
Entry DOI | 10.2210/pdb8epq/pdb |
EMDB information | 28533 |
Descriptor | Spike glycoprotein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | glycoprotein, trimer, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 |
Total number of polymer chains | 3 |
Total formula weight | 385833.01 |
Authors | Williams, J.A.,Harshbarger, W. (deposition date: 2022-10-06, release date: 2023-06-21, Last modification date: 2024-10-16) |
Primary citation | Williams, J.A.,Biancucci, M.,Lessen, L.,Tian, S.,Balsaraf, A.,Chen, L.,Chesterman, C.,Maruggi, G.,Vandepaer, S.,Huang, Y.,Mallett, C.P.,Steff, A.M.,Bottomley, M.J.,Malito, E.,Wahome, N.,Harshbarger, W.D. Structural and computational design of a SARS-CoV-2 spike antigen with improved expression and immunogenicity. Sci Adv, 9:eadg0330-eadg0330, 2023 Cited by PubMed: 37285422DOI: 10.1126/sciadv.adg0330 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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