8EPM

Human R-type voltage-gated calcium channel Cav2.3 CH2II-deleted mutant at 3.1 Angstrom resolution

8EPM の概要

• エントリーDOI: 10.2210/pdb8epm/pdb
• EMDBエントリー: 28530
• 分子名称: Voltage-dependent R-type calcium channel subunit alpha-1E, Voltage-dependent calcium channel subunit alpha-2/delta-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: cav2.3, channels, calcium ion-selective, transport protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 390020.62

構造登録者

Gao, S.,Yao, X.,Yan, N. (登録日: 2022-10-06, 公開日: 2022-12-14, 最終更新日: 2023-07-12)

• 主引用文献: Yao, X.,Wang, Y.,Wang, Z.,Fan, X.,Wu, D.,Huang, J.,Mueller, A.,Gao, S.,Hu, M.,Robinson, C.V.,Yu, Y.,Gao, S.,Yan, N.; Structures of the R-type human Ca v 2.3 channel reveal conformational crosstalk of the intracellular segments.; Nat Commun, 13:7358-7358, 2022; PubMed: 36446785; DOI: 10.1038/s41467-022-35026-6

実験手法

ELECTRON MICROSCOPY (3.1 Å)