8EPH
Crystal structure of human coagulation factor IXa (S195A), apo-form, DES-GLA
Summary for 8EPH
Entry DOI | 10.2210/pdb8eph/pdb |
Descriptor | Coagulation factor IXa light chain, Coagulation factor IXa heavy chain, alpha-L-fucopyranose, ... (5 entities in total) |
Functional Keywords | coagulation factor ix, apo form, hydrolase, blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 75471.61 |
Authors | Kolyadko, V.N.,Krishnaswamy, S. (deposition date: 2022-10-05, release date: 2024-07-03, Last modification date: 2024-07-24) |
Primary citation | Kolyadko, V.N.,Layzer, J.M.,Perry, K.,Sullenger, B.A.,Krishnaswamy, S. An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa. Proc.Natl.Acad.Sci.USA, 121:e2401136121-e2401136121, 2024 Cited by PubMed: 38985762DOI: 10.1073/pnas.2401136121 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.88 Å) |
Structure validation
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