8EM3

Carbonic Anhydrase II in complex with the diaryl urea molecule J2

8EM3 の概要

• エントリーDOI: 10.2210/pdb8em3/pdb
• 分子名称: Carbonic anhydrase 2, 4-[(3-methoxyphenyl)carbamamido]benzene-1-sulfonamide, ZINC ION, ... (4 entities in total)
• 機能のキーワード: inhibitor, caii, metal binding protein, lyase-inhibitor complex, lyase/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29675.82

構造登録者

Combs, J.,McKenna, R. (登録日: 2022-09-26, 公開日: 2023-09-27)

• 主引用文献: Debnath, J.,Keshamasetthy, D.,Combs, J.,Leon, K.,McKenna, R.; Prospective Diaryl urea: Prevent growth of breast cancer cells by inhibition and down-regulation of Carbonic Anhydrase IX.; To Be Published,

実験手法

X-RAY DIFFRACTION (1.62 Å)