8EKB

Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, deacylated P-site tRNAmet, and thermorubin at 2.70A resolution

これはPDB形式変換不可エントリーです。

8EKB の概要

• エントリーDOI: 10.2210/pdb8ekb/pdb
• 分子名称: 23S Ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (60 entities in total)
• 機能のキーワード: ribosome, antibiotic, thermorubin, trna, release factor, rapid kinetics, thermodynamics
• 由来する生物種: Escherichia coli; 詳細
• タンパク質・核酸の鎖数: 108
• 化学式量合計: 4463029.65

構造登録者

Paranjpe, M.N.,Polikanov, Y.S. (登録日: 2022-09-20, 公開日: 2022-12-21, 最終更新日: 2023-11-15)

• 主引用文献: Paranjpe, M.N.,Marina, V.I.,Grachev, A.A.,Maviza, T.P.,Tolicheva, O.A.,Paleskava, A.,Osterman, I.A.,Sergiev, P.V.,Konevega, A.L.,Polikanov, Y.S.,Gagnon, M.G.; Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin.; Nucleic Acids Res., 51:449-462, 2023; PubMed: 36546783; DOI: 10.1093/nar/gkac1189

実験手法

X-RAY DIFFRACTION (2.7 Å)