8EJ3
M. tuberculosis RNAP pause escaped complex with Bacillus subtilis NusG and GMPCPP
Summary for 8EJ3
Entry DOI | 10.2210/pdb8ej3/pdb |
EMDB information | 28174 |
Descriptor | DNA-directed RNA polymerase subunit alpha, MAGNESIUM ION, ZINC ION, ... (11 entities in total) |
Functional Keywords | transcription elongation rna polymerase pausing nusg cryo-em, transcription |
Biological source | Mycobacterium tuberculosis H37Rv More |
Total number of polymer chains | 9 |
Total formula weight | 419314.78 |
Authors | Vishwakarma, R.K.,Murakami, K.S. (deposition date: 2022-09-16, release date: 2023-02-01, Last modification date: 2024-06-19) |
Primary citation | Vishwakarma, R.K.,Qayyum, M.Z.,Babitzke, P.,Murakami, K.S. Allosteric mechanism of transcription inhibition by NusG-dependent pausing of RNA polymerase. Proc.Natl.Acad.Sci.USA, 120:e2218516120-e2218516120, 2023 Cited by PubMed: 36745813DOI: 10.1073/pnas.2218516120 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.13 Å) |
Structure validation
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