8EIK
Cryo-EM structure of human DNMT3B homo-hexamer
Summary for 8EIK
Entry DOI | 10.2210/pdb8eik/pdb |
EMDB information | 28156 28157 28158 28159 |
Descriptor | DNA (cytosine-5)-methyltransferase 3B, S-ADENOSYL-L-HOMOCYSTEINE, ZINC ION (3 entities in total) |
Functional Keywords | dna methyltransferase, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 443862.28 |
Authors | Lu, J.W.,Song, J.K. (deposition date: 2022-09-15, release date: 2023-09-20, Last modification date: 2023-12-20) |
Primary citation | Lu, J.,Fang, J.,Zhu, H.,Liang, K.L.,Khudaverdyan, N.,Song, J. Structural basis for the allosteric regulation and dynamic assembly of DNMT3B. Nucleic Acids Res., 51:12476-12491, 2023 Cited by PubMed: 37941146DOI: 10.1093/nar/gkad972 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.19 Å) |
Structure validation
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