8EHZ

Crystal structure of the STUB1 TPR domain in complex with H317, a Helicon Polypeptide

Summary for 8EHZ

Entry DOI	10.2210/pdb8ehz/pdb
Descriptor	H317, E3 ubiquitin-protein ligase CHIP, N,N'-(1,4-phenylene)diacetamide, ... (4 entities in total)
Functional Keywords	e3 ligase, complex, stapled peptide, ligase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	34707.52
Authors	Li, K.,Swiecicki, J.-M.,Tokareva, O.S.,Thomson, T.M.,Verdine, G.L.,McGee, J.H. (deposition date: 2022-09-14, release date: 2023-10-25, Last modification date: 2023-11-15)
Primary citation	Tokareva, O.S.,Li, K.,Travaline, T.L.,Thomson, T.M.,Swiecicki, J.M.,Moussa, M.,Ramirez, J.D.,Litchman, S.,Verdine, G.L.,McGee, J.H. Recognition and reprogramming of E3 ubiquitin ligase surfaces by alpha-helical peptides. Nat Commun, 14:6992-6992, 2023 Cited by PubMed: 37914719 DOI: 10.1038/s41467-023-42395-z PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.06 Å)

Structure validation