8EHH

Crystal structure of the class A extended-spectrum beta-lactamase CTX-M-96 in complex with relebactam at 1.03 Angstrom resolution

Summary for 8EHH

• Entry DOI: 10.2210/pdb8ehh/pdb
• Related: 3ZNY
• Descriptor: Beta-lactamase, (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide (3 entities in total)
• Functional Keywords: beta-lactamase inhibitor, dbo, esbl, ceftazidimase, antimicrobial protein
• Biological source: Klebsiella pneumoniae
• Total number of polymer chains: 1
• Total formula weight: 28476.22

Authors

Power, P.,Ghiglione, B.,Bonomo, R.A.,Rodriguez, M.M.,Gutkind, G.,Klinke, S. (deposition date: 2022-09-14, release date: 2023-09-20, Last modification date: 2024-03-13)

• Primary citation: Ghiglione, B.,Rodriguez, M.M.,Gutkind, G.,Bonomo, R.A.,Klinke, S.,Power, P.; Biochemical and structural evidences of the activity of relebactam as inhibitor of the extended-spectrum beta-lactamase CTX-M-96.; To be published,

Experimental method

X-RAY DIFFRACTION (1.03 Å)