8EH5

Cryo-EM structure of L9 Fab in complex with rsCSP

Summary for 8EH5

• Entry DOI: 10.2210/pdb8eh5/pdb
• EMDB information: 28135
• Descriptor: Circumsporozoite protein, L9 Heavy chain, L9 Light chain (3 entities in total)
• Functional Keywords: pfcsp, malaria, antibody, immune system
• Biological source: Plasmodium falciparum (malaria parasite P. falciparum); More
• Total number of polymer chains: 7
• Total formula weight: 174581.42

Authors

Martin, G.M.,Ward, A.B. (deposition date: 2022-09-13, release date: 2023-06-28)

• Primary citation: Martin, G.M.,Fernandez-Quintero, M.L.,Lee, W.H.,Pholcharee, T.,Eshun-Wilson, L.,Liedl, K.R.,Pancera, M.,Seder, R.A.,Wilson, I.A.,Ward, A.B.; Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9.; Nat Commun, 14:2815-2815, 2023; PubMed: 37198165; DOI: 10.1038/s41467-023-38509-2

Experimental method

ELECTRON MICROSCOPY (3.36 Å)