8EH1
Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with 4-hydroxyquinoline
Summary for 8EH1
Entry DOI | 10.2210/pdb8eh1/pdb |
Descriptor | Engineered tyrosine synthase (TmTyrS1), 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, quinolin-4-ol, ... (5 entities in total) |
Functional Keywords | tyrosine synthase, engineered enzyme, noncanonical amino acid synthase, biosynthetic protein |
Biological source | Thermotoga maritima |
Total number of polymer chains | 2 |
Total formula weight | 88404.47 |
Authors | |
Primary citation | Porter, N.J.,Almhjell, P.J.,Arnold, F.H. Noncanonical L-tyrosine synthesis by evolved tryptophan synthases To Be Published, |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
Download full validation report