8EH1

Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with 4-hydroxyquinoline

8EH1 の概要

• エントリーDOI: 10.2210/pdb8eh1/pdb
• 分子名称: Engineered tyrosine synthase (TmTyrS1), 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, quinolin-4-ol, ... (5 entities in total)
• 機能のキーワード: tyrosine synthase, engineered enzyme, noncanonical amino acid synthase, biosynthetic protein
• 由来する生物種: Thermotoga maritima
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 88404.47

構造登録者

Porter, N.J.,Almhjell, P.J.,Arnold, F.H. (登録日: 2022-09-13, 公開日: 2023-10-04)

• 主引用文献: Porter, N.J.,Almhjell, P.J.,Arnold, F.H.; Noncanonical L-tyrosine synthesis by evolved tryptophan synthases; To Be Published,

実験手法

X-RAY DIFFRACTION (2 Å)