8EGZ
Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate
Summary for 8EGZ
Entry DOI | 10.2210/pdb8egz/pdb |
Descriptor | Tryptophan synthase beta chain 1, 2-{[(E)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}prop-2-enoic acid, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | tyrosine synthase, engineered enzyme, noncanonical amino acid synthase, biosynthetic protein |
Biological source | Thermotoga maritima |
Total number of polymer chains | 2 |
Total formula weight | 88486.57 |
Authors | |
Primary citation | Porter, N.J.,Almhjell, P.J.,Arnold, F.H. Noncanonical L-tyrosine synthesis by evolved tryptophan synthases To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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