8EGN
Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa in complex with ligand AZ-13643701
8EGN の概要
エントリーDOI | 10.2210/pdb8egn/pdb |
分子名称 | UDP-N-acetylmuramate--L-alanine ligase, (1R,2S)-1-({4-[(5-tert-butyl-1-methyl-1H-pyrazol-3-yl)amino]-1H-pyrazolo[3,4-d]pyrimidin-6-yl}amino)-2,3-dihydro-1H-inden-2-ol, SULFATE ION, ... (4 entities in total) |
機能のキーワード | ssgcid, murc, udp-n-acetylmuramoyl-l-alanine synthetase, cell wall biogenesis, peptidoglycan biosynthesis, structural genomics, seattle structural genomics center for infectious disease, ligase |
由来する生物種 | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 68982.41 |
構造登録者 | Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2022-09-12, 公開日: 2022-09-28, 最終更新日: 2023-10-18) |
主引用文献 | Abendroth, J.,Dranow, D.M.,Hill, P.,Horanyi, P.S.,Lorimer, D.D.,Edwards, T.E. Crystal Structure of UDP-N-acetylmuramate-L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase, MurC) Pseudomonas aeruginosa in complex with ligand AZ-13643701 to be published, |
実験手法 | X-RAY DIFFRACTION (1.95 Å) |
構造検証レポート
検証レポート(詳細版)をダウンロード