8EEW

CryoEM of the soluble OPA1 dimer from the GDP-AlFx bound helical assembly on a lipid membrane

8EEW の概要

• エントリーDOI: 10.2210/pdb8eew/pdb
• EMDBエントリー: 28063
• 分子名称: Dynamin-like 120 kDa protein, form S1, GUANOSINE-5'-DIPHOSPHATE, TETRAFLUOROALUMINATE ION, ... (5 entities in total)
• 機能のキーワード: gtpase, dynamin-family protein, mitochondrial fusion protein, mitochondria, optic atrophy, lipid binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 179744.19

構造登録者

Nyenhuis, S.B.,Wu, X.,Stanton, A.E.,Strub, M.P.,Yim, Y.I.,Canagarajah, B.,Hinshaw, J.E. (登録日: 2022-09-07, 公開日: 2023-06-28, 最終更新日: 2023-09-13)

• 主引用文献: Nyenhuis, S.B.,Wu, X.,Strub, M.P.,Yim, Y.I.,Stanton, A.E.,Baena, V.,Syed, Z.A.,Canagarajah, B.,Hammer, J.A.,Hinshaw, J.E.; OPA1 helical structures give perspective to mitochondrial dysfunction.; Nature, 620:1109-1116, 2023; PubMed: 37612506; DOI: 10.1038/s41586-023-06462-1

実験手法

ELECTRON MICROSCOPY (5.48 Å)