8EDZ

The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ000986319

Summary for 8EDZ

• Entry DOI: 10.2210/pdb8edz/pdb
• Descriptor: Polymerase acidic protein, benzyl [2-(6-{[2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)ethyl]carbamoyl}-5-hydroxy-4-oxo-1,4-dihydropyrimidin-2-yl)propan-2-yl]carbamate, Hexa Vinylpyrrolidone K15, ... (6 entities in total)
• Functional Keywords: nuclease, influenza, inhibitor resistance, viral protein
• Biological source: Influenza A virus (A/Luxembourg/43/2009(H1N1)); More
• Total number of polymer chains: 1
• Total formula weight: 24517.61

Authors

Cuypers, M.G.,Slavish, J.P.,Jayaraman, S.,Rankovic, Z.,White, S.W. (deposition date: 2022-09-06, release date: 2022-10-05, Last modification date: 2023-10-18)

• Primary citation: Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W.; The crystal structure of I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ000986319; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.65 Å)