8EAY
HMPV F complex with 4I3 Fab
Summary for 8EAY
Entry DOI | 10.2210/pdb8eay/pdb |
EMDB information | 27808 27990 |
Descriptor | Fusion glycoprotein F0, 4I3 heavy chain protein, 4I3 light chain protein (3 entities in total) |
Functional Keywords | human antibodies, rsv and mpv fusion protein, complex cryo-em structure, viral protein and antiviral protein, biosynthetic protein |
Biological source | Human metapneumovirus A (human) More |
Total number of polymer chains | 3 |
Total formula weight | 69859.11 |
Authors | Wen, X.,Jardetzky, T.S. (deposition date: 2022-08-30, release date: 2023-08-16, Last modification date: 2023-08-23) |
Primary citation | Wen, X.,Suryadevara, N.,Kose, N.,Liu, J.,Zhan, X.,Handal, L.S.,Williamson, L.E.,Trivette, A.,Carnahan, R.H.,Jardetzky, T.S.,Crowe Jr., J.E. Potent cross-neutralization of respiratory syncytial virus and human metapneumovirus through a structurally conserved antibody recognition mode. Cell Host Microbe, 31:1288-1300.e6, 2023 Cited by PubMed: 37516111DOI: 10.1016/j.chom.2023.07.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.33 Å) |
Structure validation
Download full validation report