8E87
Human DNA polymerase eta-DNA-rA-ended primer-dGMPNPP ternary mismatch complex with Mg2+
Summary for 8E87
Entry DOI | 10.2210/pdb8e87/pdb |
Descriptor | DNA polymerase eta, DNA (5'-D(*CP*AP*TP*TP*TP*TP*GP*AP*CP*GP*CP*T)-3'), DNA/RNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*A)-3'), ... (6 entities in total) |
Functional Keywords | dna polymerase, transferase, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 55252.52 |
Authors | |
Primary citation | Chang, C.,Lee Luo, C.,Eleraky, S.,Lin, A.,Zhou, G.,Gao, Y. Primer terminal ribonucleotide alters the active site dynamics of DNA polymerase eta and reduces DNA synthesis fidelity. J.Biol.Chem., 299:102938-102938, 2023 Cited by PubMed: 36702254DOI: 10.1016/j.jbc.2023.102938 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
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