8E7P

Staphylococcus aureus ClpP in complex with compound 3421

8E7P の概要

• エントリーDOI: 10.2210/pdb8e7p/pdb
• 関連するPDBエントリー: 8E71
• 分子名称: ATP-dependent Clp protease proteolytic subunit, (4S)-2-METHYL-2,4-PENTANEDIOL, (5R,6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-8-[(naphthalen-1-yl)methyl]-4,7-dioxohexahydro-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide, ... (4 entities in total)
• 機能のキーワード: clpp, cytosolic protein, hydrolase
• 由来する生物種: Staphylococcus aureus subsp. aureus NCTC 8325
• タンパク質・核酸の鎖数: 14
• 化学式量合計: 325412.43

構造登録者

Lee, R.E.,Griffith, E.C. (登録日: 2022-08-24, 公開日: 2023-07-05, 最終更新日: 2023-10-25)

• 主引用文献: Singh, A.C.,Zhao, Y.,Griffith, E.C.,Tangallapally, R.,Jarret, M.W.,Lee, R.E.; Development of a high throughput and site specific, fluorescent polarization assay to screen for activators of Caseinolytic Protease P leads to the discovery of synthetically tractable new activator class; To Be Published,

実験手法

X-RAY DIFFRACTION (1.68 Å)