8E6J

3H03 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)

8E6J の概要

• エントリーDOI: 10.2210/pdb8e6j/pdb
• EMDBエントリー: 27920
• 分子名称: Neuraminidase, 3H03 fragment antigen binding light chain, 3H03 fragment antigen binding heavy chain (3 entities in total)
• 機能のキーワード: influenza, monoclonal antibody, na, h1n1, cross-reactive antibody, viral protein
• 由来する生物種: Influenza A virus (A/Brevig Mission/1/1918(H1N1)); 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 390290.30

構造登録者

Turner, H.L.,Ozorowski, G.,Ward, A.B. (登録日: 2022-08-22, 公開日: 2023-08-09, 最終更新日: 2023-08-23)

• 主引用文献: Hansen, L.,McMahon, M.,Turner, H.L.,Zhu, X.,Turner, J.S.,Ozorowski, G.,Stadlbauer, D.,Vahokoski, J.,Schmitz, A.J.,Rizk, A.A.,Alsoussi, W.B.,Strohmeier, S.,Yu, W.,Choreno-Parra, J.A.,Jimenez-Alvarez, L.,Cruz-Lagunas, A.,Zuniga, J.,Mudd, P.A.,Cox, R.J.,Wilson, I.A.,Ward, A.B.,Ellebedy, A.H.,Krammer, F.; Human anti-N1 monoclonal antibodies elicited by pandemic H1N1 virus infection broadly inhibit HxN1 viruses in vitro and in vivo.; Immunity, 56:1927-1938.e8, 2023; PubMed: 37506693; DOI: 10.1016/j.immuni.2023.07.004

実験手法

ELECTRON MICROSCOPY (2.7 Å)