8E5E
Crystal structure of double-stranded DNA deaminase toxin DddA in complex with DNA with the target cytosine flipped into the active site
Summary for 8E5E
Entry DOI | 10.2210/pdb8e5e/pdb |
Descriptor | Double-stranded DNA deaminase toxin A, DNA (5'-D(*GP*TP*AP*CP*CP*GP*GP*AP*CP*GP*TP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*AP*CP*GP*TP*CP*CP*GP*GP*TP*AP*C)-3'), ... (6 entities in total) |
Functional Keywords | toxin, dna binding, deaminase, toxin-dna complex, toxin/dna |
Biological source | Burkholderia cenocepacia More |
Total number of polymer chains | 3 |
Total formula weight | 23338.50 |
Authors | Yin, L.,Shi, K.,Aihara, H. (deposition date: 2022-08-21, release date: 2023-05-24, Last modification date: 2024-09-18) |
Primary citation | Yin, L.,Shi, K.,Aihara, H. Structural basis of sequence-specific cytosine deamination by double-stranded DNA deaminase toxin DddA. Nat.Struct.Mol.Biol., 30:1153-1159, 2023 Cited by PubMed: 37460895DOI: 10.1038/s41594-023-01034-3 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.62 Å) |
Structure validation
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