8E1Q

The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044

8E1Q の概要

• エントリーDOI: 10.2210/pdb8e1q/pdb
• 分子名称: Polymerase acidic protein, MANGANESE (II) ION, 5-hydroxy-N-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-6-oxo-2-{[2-(trifluoromethyl)phenyl]methyl}-1,6-dihydropyrimidine-4-carboxamide, ... (6 entities in total)
• 機能のキーワード: nuclease, influenza, inhibitor resistance, viral protein
• 由来する生物種: Influenza A virus (A/Luxembourg/43/2009(H1N1)); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 24570.56

構造登録者

Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W. (登録日: 2022-08-11, 公開日: 2022-09-14, 最終更新日: 2023-10-18)

• 主引用文献: Cuypers, M.G.,Slavish, J.P.,Rankovic, Z.,White, S.W.; The crystal structure of the I38T mutant PA endonuclease (2009/H1N1/CALIFORNIA) in complex with compound SJ001023044; To Be Published,

実験手法

X-RAY DIFFRACTION (2.5 Å)