8DY6

Vaccine elicited Antibody MU89+S27Y bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer

This is a non-PDB format compatible entry.

Summary for 8DY6

• Entry DOI: 10.2210/pdb8dy6/pdb
• Related: 8DTO
• EMDB information: 27776
• Descriptor: Envelope glycoprotein gp160, 2-acetamido-2-deoxy-beta-D-glucopyranose, MU89+S27Y Heavy Chain, ... (10 entities in total)
• Functional Keywords: hiv-1 envelope, vaccine-induced antibody, broadly neutralizing antibody, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 12
• Total formula weight: 542090.67

Authors

Stalls, V.,Acharya, P. (deposition date: 2022-08-03, release date: 2023-04-19, Last modification date: 2024-05-22)

• Primary citation: Wiehe, K.,Saunders, K.O.,Stalls, V.,Cain, D.W.,Venkatayogi, S.,Martin Beem, J.S.,Berry, M.,Evangelous, T.,Henderson, R.,Hora, B.,Xia, S.M.,Jiang, C.,Newman, A.,Bowman, C.,Lu, X.,Bryan, M.E.,Bal, J.,Sanzone, A.,Chen, H.,Eaton, A.,Tomai, M.A.,Fox, C.B.,Tam, Y.K.,Barbosa, C.,Bonsignori, M.,Muramatsu, H.,Alam, S.M.,Montefiori, D.C.,Williams, W.B.,Pardi, N.,Tian, M.,Weissman, D.,Alt, F.W.,Acharya, P.,Haynes, B.F.; Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction.; Cell Host Microbe, 32:693-709.e7, 2024; PubMed: 38670093; DOI: 10.1016/j.chom.2024.04.006

Experimental method

ELECTRON MICROSCOPY (4.32 Å)