8DXS

Cryo-EM structure of RBD-directed neutralizing antibody P2B4 in complex with prefusion SARS-CoV-2 spike glycoprotein

Summary for 8DXS

• Entry DOI: 10.2210/pdb8dxs/pdb
• EMDB information: 27775
• Descriptor: Spike glycoprotein, P2B4 Heavy chain, P2B4 Light chain, ... (4 entities in total)
• Functional Keywords: neutralizing antibody, fusion protein, spike glycoprotein, covid-19, rbd, rbd-directed antibody, p2b4, viral protein, immune system, viral protein-immune system complex, viral protein/immune system
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 9
• Total formula weight: 578863.38

Authors

Reddem, E.R.,Shapiro, L. (deposition date: 2022-08-03, release date: 2022-12-07, Last modification date: 2023-01-18)

• Primary citation: Luo, M.,Zhou, B.,Reddem, E.R.,Tang, B.,Chen, B.,Zhou, R.,Liu, H.,Liu, L.,Katsamba, P.S.,Au, K.K.,Man, H.O.,To, K.K.,Yuen, K.Y.,Shapiro, L.,Dang, S.,Ho, D.D.,Chen, Z.; Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2.; Emerg Microbes Infect, 12:2146538-2146538, 2023; PubMed: 36354024; DOI: 10.1080/22221751.2022.2146538

Experimental method

ELECTRON MICROSCOPY (3.76 Å)