8DWX

Chikungunya VLP in complex with neutralizing Fab 506.C01 (asymmetric unit)

8DWX の概要

• エントリーDOI: 10.2210/pdb8dwx/pdb
• EMDBエントリー: 27765
• 分子名称: E1 glycoprotein, E2 glycoprotein, Capsid protein, ... (6 entities in total)
• 機能のキーワード: antibody, viral protein-immune system complex, csgid, structural genomics, center for structural genomics of infectious diseases, viral protein/immune system
• 由来する生物種: Chikungunya virus strain Senegal 37997; 詳細
• タンパク質・核酸の鎖数: 20
• 化学式量合計: 547587.23

構造登録者

Adams, L.J.,Fremont, D.H.,Center for Structural Genomics of Infectious Diseases (CSGID) (登録日: 2022-08-02, 公開日: 2023-05-31)

• 主引用文献: Raju, S.,Adams, L.J.,Earnest, J.T.,Warfield, K.,Vang, L.,Crowe Jr., J.E.,Fremont, D.H.,Diamond, M.S.; A chikungunya virus-like particle vaccine induces broadly neutralizing and protective antibodies against alphaviruses in humans.; Sci Transl Med, 15:eade8273-eade8273, 2023; PubMed: 37196061; DOI: 10.1126/scitranslmed.ade8273

実験手法

ELECTRON MICROSCOPY (3.27 Å)