8DWR

Crystal structure of the L333V variant of catalase-peroxidase from Mycobacterium tuberculosis

Summary for 8DWR

• Entry DOI: 10.2210/pdb8dwr/pdb
• Related: 1SJ2 2CCA
• Descriptor: Catalase-peroxidase, PROTOPORPHYRIN IX CONTAINING FE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (6 entities in total)
• Functional Keywords: catalase-peroxidase, katg, oxidoreductase, heme
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 4
• Total formula weight: 330249.73

Authors

Diaz-Vilchis, A.,Uribe-Vazquez, B.,Avila-Linares, A.,Rudino-Pinera, E.,Soberon, X. (deposition date: 2022-08-01, release date: 2023-08-02, Last modification date: 2024-03-13)

• Primary citation: Uribe-Vazquez, B.,Diaz-Vilchis, A.,Avila-Linares, A.,Saab-Rincon, G.,Marin-Tovar, Y.,Flores, H.,Pastor, N.,Huerta-Miranda, G.,Rudino-Pinera, E.,Soberon, X.; Characterization of a catalase-peroxidase variant (L333V-KatG) identified in an INH-resistant Mycobacterium tuberculosis clinical isolate.; Biochem Biophys Rep, 37:101649-101649, 2024; PubMed: 38318524; DOI: 10.1016/j.bbrep.2024.101649

Experimental method

X-RAY DIFFRACTION (2.1 Å)