8DWM

Host-guest complex of bleomycin A2 fully bound to CTTAGTTATAACTAAG

8DWM の概要

• エントリーDOI: 10.2210/pdb8dwm/pdb
• 分子名称: reverse transcriptase, DNA (5'-D(*CP*TP*TP*AP*GP*TP*TP*A)-3'), DNA (5'-D(P*TP*AP*AP*CP*TP*AP*AP*G)-3'), ... (6 entities in total)
• 機能のキーワード: host-guest complex, moloney murine leukemia virus reverse transcriptase, bleomycin a2, dna structure, dna binding protein-dna complex, dna binding protein/dna
• 由来する生物種: Moloney murine leukemia virus; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36350.28

構造登録者

Georgiadis, M.M. (登録日: 2022-08-01, 公開日: 2023-01-11, 最終更新日: 2023-10-25)

• 主引用文献: Goodwin, K.D.,Lewis, M.A.,Long, E.C.,Georgiadis, M.M.; Two distinct rotations of bithiazole DNA intercalation revealed by direct comparison of crystal structures of Co(III)•bleomycin A 2 and B 2 bound to duplex 5'-TAGTT sites.; Bioorg.Med.Chem., 77:117113-117113, 2023; PubMed: 36516684; DOI: 10.1016/j.bmc.2022.117113

実験手法

X-RAY DIFFRACTION (2.99 Å)