8DWA

Crystal structure of neutralizing antibody P1D9 Fab in complex with SARS-CoV-2 spike receptor binding domain (RBD)

8DWA の概要

• エントリーDOI: 10.2210/pdb8dwa/pdb
• 分子名称: Spike protein S1, P1D9 Heavy chain, P1D9 Light chain, ... (4 entities in total)
• 機能のキーワード: covid-19, sars-cov-2, viral protein, spike glycoprotein, receptor binding protein, rbd, neutralizing antibody, 10-28, fab, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 66463.23

構造登録者

Reddem, E.R.,Shapiro, L. (登録日: 2022-08-01, 公開日: 2022-12-07, 最終更新日: 2023-10-25)

• 主引用文献: Luo, M.,Zhou, B.,Reddem, E.R.,Tang, B.,Chen, B.,Zhou, R.,Liu, H.,Liu, L.,Katsamba, P.S.,Au, K.K.,Man, H.O.,To, K.K.,Yuen, K.Y.,Shapiro, L.,Dang, S.,Ho, D.D.,Chen, Z.; Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2.; Emerg Microbes Infect, 12:2146538-2146538, 2023; PubMed: 36354024; DOI: 10.1080/22221751.2022.2146538

実験手法