8DVU
Cryo-EM structure of RIG-I bound to the internal sites of OHSLR30 (+ATP)
Summary for 8DVU
Entry DOI | 10.2210/pdb8dvu/pdb |
EMDB information | 27745 |
Descriptor | Antiviral innate immune response receptor RIG-I, OHSLR30, ZINC ION, ... (5 entities in total) |
Functional Keywords | ribonucleoprotein complex, rna sensor, rig-i like receptor, hydrolase-rna complex, hydrolase/rna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 127806.67 |
Authors | Wang, W.,Pyle, A.M. (deposition date: 2022-07-29, release date: 2022-11-16, Last modification date: 2024-06-12) |
Primary citation | Wang, W.,Pyle, A.M. The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands. Mol.Cell, 82:4131-4144.e6, 2022 Cited by PubMed: 36272408DOI: 10.1016/j.molcel.2022.09.029 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.9 Å) |
Structure validation
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