8DT2
X-ray structure of human acetylcholinesterase inhibited by paraoxon (POX-hAChE)
Summary for 8DT2
| Entry DOI | 10.2210/pdb8dt2/pdb |
| Descriptor | Acetylcholinesterase, DIETHYL PHOSPHONATE, GLYCEROL, ... (5 entities in total) |
| Functional Keywords | acetylcholine hydrolysis, hydrolase |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 121376.80 |
| Authors | Kovalevsky, A.Y.,Gerlits, O.,Radic, Z. (deposition date: 2022-07-25, release date: 2022-11-02, Last modification date: 2023-10-18) |
| Primary citation | Gerlits, O.,Fajer, M.,Cheng, X.,Blumenthal, D.K.,Radic, Z.,Kovalevsky, A. Structural and dynamic effects of paraoxon binding to human acetylcholinesterase by X-ray crystallography and inelastic neutron scattering. Structure, 30:1538-1549.e3, 2022 Cited by PubMed: 36265484DOI: 10.1016/j.str.2022.09.006 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.803 Å) |
Structure validation
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