8DSK

Structure of the N358Y variant of serine hydroxymethyltransferase 8 in complex with PLP, glycine, and formyl tetrahydrofolate

8DSK の概要

• エントリーDOI: 10.2210/pdb8dsk/pdb
• 分子名称: Serine hydroxymethyltransferase, N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... (5 entities in total)
• 機能のキーワード: enzyme, complex, transferase
• 由来する生物種: Glycine max (soybean)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 220444.94

構造登録者

Korasick, D.A.,Beamer, L.J. (登録日: 2022-07-22, 公開日: 2023-10-18, 最終更新日: 2024-01-31)

• 主引用文献: Korasick, D.A.,Owuocha, L.F.,Kandoth, P.K.,Tanner, J.J.,Mitchum, M.G.,Beamer, L.J.; Structural and functional analysis of two SHMT8 variants associated with soybean cyst nematode resistance.; Febs J., 291:323-337, 2024; PubMed: 37811683; DOI: 10.1111/febs.16971

実験手法

X-RAY DIFFRACTION (1.63 Å)