8DOV

Crystal structure of the Shr Hemoglobin Interacting Domain 2 (HID2) in complex with Hemoglobin

8DOV の概要

• エントリーDOI: 10.2210/pdb8dov/pdb
• 分子名称: Hemoglobin subunit alpha, Hemoglobin subunit beta, Heme-binding protein Shr, ... (6 entities in total)
• 機能のキーワード: duf1533, hemoglobin, heme, hid, complex, beta-sandwich, globin, shr, transport protein
• 由来する生物種: Streptococcus pyogenes; 詳細
• タンパク質・核酸の鎖数: 11
• 化学式量合計: 166414.19

構造登録者

Macdonald, R.,Mahoney, B.J.,Cascio, D.,Clubb, R.T. (登録日: 2022-07-14, 公開日: 2023-01-25, 最終更新日: 2023-10-25)

• 主引用文献: Macdonald, R.,Mahoney, B.J.,Soule, J.,Goring, A.K.,Ford, J.,Loo, J.A.,Cascio, D.,Clubb, R.T.; The Shr receptor from Streptococcus pyogenes uses a cap and release mechanism to acquire heme-iron from human hemoglobin.; Proc.Natl.Acad.Sci.USA, 120:e2211939120-e2211939120, 2023; PubMed: 36693107; DOI: 10.1073/pnas.2211939120

実験手法

X-RAY DIFFRACTION (2.1 Å)