8DMR

Legionella macrodomain effector MavL R370A in complex with ADP-ribose

Summary for 8DMR

• Entry DOI: 10.2210/pdb8dmr/pdb
• Descriptor: MavL, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, 1,2-ETHANEDIOL, ... (7 entities in total)
• Functional Keywords: complex, macrodomain, metaeffector, antitoxin
• Biological source: Legionella pneumophila
• Total number of polymer chains: 1
• Total formula weight: 45003.17

Authors

Zhang, Z.,Das, C. (deposition date: 2022-07-08, release date: 2023-07-12, Last modification date: 2024-07-24)

• Primary citation: Zhang, Z.,Fu, J.,Rack, J.G.M.,Li, C.,Voorneveld, J.,Filippov, D.V.,Ahel, I.,Luo, Z.Q.,Das, C.; Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.; Nat Commun, 15:2452-2452, 2024; PubMed: 38503748; DOI: 10.1038/s41467-024-46649-2

Experimental method

X-RAY DIFFRACTION (1.86 Å)