8DM4

Cryo-EM structure of SARS-CoV-2 Omicron BA.2 spike protein in complex with Fab 4A8 (focused refinement of NTD and 4A8)

8DM4 の概要

• エントリーDOI: 10.2210/pdb8dm4/pdb
• EMDBエントリー: 27526
• 分子名称: Spike glycoprotein, Fab 4A8 heavy chain, Fab 4A8 light chain, ... (5 entities in total)
• 機能のキーワード: sars-cov-2, glycoprotein, fusion protein, viral protein, viral protein-immune system complex, omicron, ba.2, 4a8, viral protein/immune system
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2; 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 197226.99

構造登録者

Zhu, X.,Saville, J.W.,Mannar, D.,Berezuk, A.M.,Cholak, S.,Tuttle, K.S.,Vahdatihassani, F.,Subramaniam, S. (登録日: 2022-07-08, 公開日: 2023-01-25)

• 主引用文献: Saville, J.W.,Mannar, D.,Zhu, X.,Berezuk, A.M.,Cholak, S.,Tuttle, K.S.,Vahdatihassani, F.,Subramaniam, S.; Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein.; Cell Rep, 42:111964-111964, 2023; PubMed: 36640338; DOI: 10.1016/j.celrep.2022.111964

実験手法

ELECTRON MICROSCOPY (2.45 Å)