8DK4

Peroxisome proliferator-activated receptor gamma in complex with VSP-51-2

8DK4 の概要

• エントリーDOI: 10.2210/pdb8dk4/pdb
• 分子名称: Peroxisome proliferator-activated receptor gamma, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, 5-(benzylcarbamoyl)-1-[(4-chloro-3-fluorophenyl)methyl]-1H-indole-2-carboxylic acid, ... (4 entities in total)
• 機能のキーワード: peroxisome proliferator-activated receptor gamma, modulator, vsp-51-2, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 33125.93

構造登録者

Ma, L.,Zhou, X.E.,Suino-Powell, K.,Hou, N.,Zhou, Z.,Luo, J.,Xu, H.E.,Yi, W. (登録日: 2022-07-02, 公開日: 2023-07-05, 最終更新日: 2023-10-25)

• 主引用文献: Ma, L.,Zhou, X.E.,Suino-Powell, K.,Hou, N.,Zhou, Z.,Luo, J.,Xu, H.E.,Yi, W.; Identification of VSP-51-2 as the Novel and Safe PPAR gamma Modulator: Structure-Based Design, Biological Validation and Crystal Analysis; To Be Published,

実験手法

X-RAY DIFFRACTION (2.6 Å)