8DIN

The complex structure between human IgG1 Fc and its high affinity receptor FcgRI H174R variant

8DIN の概要

• エントリーDOI: 10.2210/pdb8din/pdb
• 分子名称: Ig gamma-1 Fc chain, High affinity immunoglobulin gamma Fc receptor I, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: high affinity igg1 fc receptor, immune system
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 83874.51

構造登録者

Lu, J.,Sun, P.D. (登録日: 2022-06-29, 公開日: 2023-05-10, 最終更新日: 2023-10-25)

• 主引用文献: Lu, J.,Spencer, M.,Zou, Z.,Traver, M.,Brzostowski, J.,Sun, P.D.; Fc gamma RI FG-loop functions as a pH sensitive switch for IgG binding and release.; Front Immunol, 14:1100499-1100499, 2023; PubMed: 36814926; DOI: 10.3389/fimmu.2023.1100499

実験手法

X-RAY DIFFRACTION (2.5 Å)