8DGP

14-3-3 epsilon bound to phosphorylated PEAK3 (pS69) peptide

Summary for 8DGP

Entry DOI	10.2210/pdb8dgp/pdb
Descriptor	14-3-3 protein epsilon, Phosphorylated PEAK3 (pS69) peptide, 1,2-ETHANEDIOL, ... (5 entities in total)
Functional Keywords	signaling protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	128208.58
Authors	Roy, M.J.,Hardy, J.M.,Lucet, I.S. (deposition date: 2022-06-24, release date: 2023-06-07, Last modification date: 2023-10-25)
Primary citation	Roy, M.J.,Surudoi, M.G.,Kropp, A.,Hou, J.,Dai, W.,Hardy, J.M.,Liang, L.Y.,Cotton, T.R.,Lechtenberg, B.C.,Dite, T.A.,Ma, X.,Daly, R.J.,Patel, O.,Lucet, I.S. Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling. Nat Commun, 14:3542-3542, 2023 Cited by PubMed: 37336884 DOI: 10.1038/s41467-023-38869-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation