8DFL
Structure of human Kv1.3 with A0194009G09 nanobodies (alternate conformation)
Summary for 8DFL
Entry DOI | 10.2210/pdb8dfl/pdb |
EMDB information | 25417 |
Descriptor | Potassium voltage-gated channel subfamily A member 3,Green fluorescent protein fusion, Nanobody A0194009G09, POTASSIUM ION (3 entities in total) |
Functional Keywords | ion channel, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 8 |
Total formula weight | 435589.09 |
Authors | Meyerson, J.R.,Selvakumar, P. (deposition date: 2022-06-22, release date: 2022-07-13, Last modification date: 2024-05-01) |
Primary citation | Selvakumar, P.,Fernandez-Marino, A.I.,Khanra, N.,He, C.,Paquette, A.J.,Wang, B.,Huang, R.,Smider, V.V.,Rice, W.J.,Swartz, K.J.,Meyerson, J.R. Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. Nat Commun, 13:3854-3854, 2022 Cited by PubMed: 35788586DOI: 10.1038/s41467-022-31285-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.25 Å) |
Structure validation
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