8DE9

Cryo-EM structure of the zebrafish two pore domain K+ channel TREK1 (K2P2.1) in DDM/POPE mixed micelles

8DE9 の概要

• エントリーDOI: 10.2210/pdb8de9/pdb
• EMDBエントリー: 27388
• 分子名称: Potassium channel, subfamily K, member 2a, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, POTASSIUM ION (3 entities in total)
• 機能のキーワード: ion channel, k2p, k2p2.1, trek1, trek-1, pope, membrane protein
• 由来する生物種: Danio rerio (zebrafish)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 71956.07

構造登録者

Schmidpeter, P.A.M.,Nimigean, C.M.,Riegelhaupt, P.M. (登録日: 2022-06-20, 公開日: 2023-03-08)

• 主引用文献: Schmidpeter, P.A.M.,Petroff 2nd, J.T.,Khajoueinejad, L.,Wague, A.,Frankfater, C.,Cheng, W.W.L.,Nimigean, C.M.,Riegelhaupt, P.M.; Membrane phospholipids control gating of the mechanosensitive potassium leak channel TREK1.; Nat Commun, 14:1077-1077, 2023; PubMed: 36841877; DOI: 10.1038/s41467-023-36765-w

実験手法

ELECTRON MICROSCOPY (3.4 Å)