8DDW
cryo-EM structure of TRPM3 ion channel in complex with Gbg, tethered by ALFA-nanobody
Summary for 8DDW
Entry DOI | 10.2210/pdb8ddw/pdb |
Related | 8DDQ 8DDR 8DDS 8DDT 8DDU 8DDV |
EMDB information | 27344 |
Descriptor | Transient receptor potential cation channel, subfamily M, member 3, Unidentified segment at the N-terminus of TRPM3, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (4 entities in total) |
Functional Keywords | trpm3, ion channel, gbg, membrane protein |
Biological source | Mus musculus (house mouse) More |
Total number of polymer chains | 10 |
Total formula weight | 682110.49 |
Authors | Zhao, C.,MacKinnon, R. (deposition date: 2022-06-19, release date: 2022-11-02, Last modification date: 2024-06-12) |
Primary citation | Zhao, C.,MacKinnon, R. Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Neuron, 111:81-, 2023 Cited by PubMed: 36283409DOI: 10.1016/j.neuron.2022.10.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.7 Å) |
Structure validation
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