8DBB

Crystal structure of DDT with the selective inhibitor 2,5-Pyridinedicarboxylic Acid

8DBB の概要

• エントリーDOI: 10.2210/pdb8dbb/pdb
• 分子名称: D-dopachrome decarboxylase, pyridine-2,5-dicarboxylic acid, CITRIC ACID, ... (4 entities in total)
• 機能のキーワード: trimeric, inhibitor, complex, enzyme, lyase-inhibitor complex, lyase/inhibitor
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 38867.65

構造登録者

Parkins, A.,Banumathi, S.,Pantouris, G. (登録日: 2022-06-14, 公開日: 2023-03-08, 最終更新日: 2023-10-25)

• 主引用文献: Parkins, A.,Das, P.,Prahaladan, V.,Rangel, V.M.,Xue, L.,Sankaran, B.,Bhandari, V.,Pantouris, G.; 2,5-Pyridinedicarboxylic acid is a bioactive and highly selective inhibitor of D-dopachrome tautomerase.; Structure, 31:355-, 2023; PubMed: 36805127; DOI: 10.1016/j.str.2023.01.008

実験手法

X-RAY DIFFRACTION (1.3 Å)